Nonclinical and Clinical ServicesWe have renewed our web page for Nonclinical Services. Please find the link hereWe have renewed our web page for Chemical Substance Management. Please find the link here

Cell Function Research

Cell Function Research

In Vitro Phospholipidosis Screening

We perform in vitro phospholipidosis screening tests in CHL cells. Please contact us for more information.

Phospholipidosis Amiodarone 10μmol/L

Phospholipidosis Amiodarone 10μmol/L

Phospholipidosis Control

Phospholipidosis Control

In Vitro Hepatotoxicity Screening

We perform hepatotoxicity screening tests in primary cultured hepatocytes of various species based on experience in rat primary cultured hepatocytes and human cultured hepatocytes through the Toxicogenomics Project in Japan (2002-2006). Please contact us for more information.

Hepatotoxicity CCl4 5000 μmol/L

Hepatotoxicity CCl4 5000 μmol/L

Hepatotoxicity Control

Hepatotoxicity Control

Photocytotoxicity Tests

We perform GLP tests in compliance with the OECD guideline 432 and screening tests with high throughputs.

New Research Field

Cellomics® ArrayScanVTI

Cellomics® ArrayScanVTI

  • Development of new evaluation system for cardiotoxicity

    We have been engaging in development of highly functional test systems using human stem cell-derived myocardial cells, which can replace existing methods (hERG-HEK test and APD measurement using animal heart), in collaboration with universities.

  • Development of new evaluation system for hepatotoxicity

    We are also engaging in development of highly functional in vitro test systems for hepatotoxicity in collaboration with universities.

  • Development of High-Content Screening Methods

    We have newly introduced Cellomics ArrayScan® VTI (Thermo Fisher Scientific Inc.). This instrument allows evaluations of function changes in each cell over desired features and time course to meet the needs of clients.

All of our research and studies are in strict adherence to the laws concerning protection and management of animals with full respect of the standards concerning care and management of test animals, and have been accepted and certified for animal welfare practices.



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