Nonclinical and Clinical ServicesWe have renewed our web page for Nonclinical Services. Please find the link here

Nonclinical Studies

The Toxicological Science Division serves to perform nonclinical studies by taking full advantages of a vast array of techniques and renowned reliability that the former Mitsubishi Chemical Safety Institute Ltd. (MSI) had acquired through its broad range of accumulated experience.

Tests on Chemical Substances

Tests and Studies to Meet the Requirements of the Chemical Substances Control Law

  • Biodegradation Tests
  • Bioaccumulation Tests
  • Partition Coefficient (Pow) Measurement
  • Reverse Mutation Tests (Ames Tests)
  • Chromosomal Aberration Tests
  • Repeated Dose Toxicity Tests
  • Polymer Flow Scheme Tests
  • Ecotoxicity Studies
  • For details

Tests and Studies to Meet the Requirements of the Industrial Safety and Hygiene Law

  • Bacterial Mutation Tests (Ames Tests)
  • Chromosomal Aberration Tests
  • For details

Notification Service for New Chemical Substances

Ecotoxicity Studies

  • Growth Inhibition and Recovery Tests in Freshwater Alga and Cyanobacteria
  • Acute Immobilization Tests in Water Fleas
  • Reproduction Tests in Water Fleas
  • Acute Toxicity Tests in Fish
  • Prolonged Toxicity Tests in Fish
  • Early-Life Stage Toxicity (ELST) Tests in Fish
  • Bioconcentration: Flow-through Fish Tests
  • Activated Sludge, Respiration Inhibition Tests
  • Acute Toxicity Tests in Earthworms
  • Acute Toxicity Tests in Freshwater shrimp (Paratya Compressa Improvisa)
  • Sediment-Water Chironomid Toxicity Using Spiked Sediment
  • Others(Enviranmental impact assessment of biotechnology., bioassay of drainage/enviromental water)
  • For details

Risk Evaluation

  • Information Research and Analysis of Chemicals, Agrochemicals, Pharmaceuticals, etc.
  • Document Preparation for Submission to OECD/ICCA HPV Chemicals Programs and Storage of Chemical Substance Data in IUCLID
  • Risk Assessment and Analysis of Chemicals
  • Preparation of Risk Assessment Reports
  • Others
  • For details

All of our research and studies are in strict adherence to the laws concerning protection and management of animals with full respect of the standards concerning care and management of test animals, and have been accepted and certified for animal welfare practices.



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