Nonclinical and Clinical ServicesWe have renewed our web page for Nonclinical Services. Please find the link hereWe have renewed our web page for Chemical Substance Management. Please find the link here

Genomic Research

Pharmacogenomics (PGx)

PGx Test Flow

Toxicogenomics (TGx)

TGx Test Flow

Banking Service

The banking service includes sample collection, anonimization, DNA extraction, and storage/management. Our banking rooms require ID cards and are inaccessible to unauthorized personnel. Moreover, they are strictly temperature controlled 24 hours a day by an integrated temperature control system. All samples are given an anonymous identification code (two-dimensional bar code).

Features of our banking service
  1. Samples are stored at our GLP-compliant facilities, which allows for long term storage and management.
  2. Test protocol is available.
  3. QA inspection is available as an option (please contact us for more information).
  4. Samples are stored in GLP-compliant storage (deep freezer [-80℃]) equipped with an emergency power source.
  5. Samples are anonymized, stored, and managed under control of the genebank administrator.
  6. Receipt of samples from overseas is available.
  7. Sample shipping is available.
  8. Flexible storage system is available; after DNA extraction*, blood or plasma dividing, etc.

    * DNA extraction: QIAamp DNA kit (Qiagen), etc.

Gene Expression Profiling

We analyze RNA quality in samples (tissue, cell, and RNA [total RNA] samples) before conducting gene expression profiling. Various services are available at your request, including cluster analyses with GeneSpring GX software. We are an authorized service provider of Affymetrix, Inc.

  1. Gene Expression Profiling with DNA Microarray

    We are entrusted with gene expression profiling of various species with Affymetrix GeneChip®. Profiling with Agilent DNA Microarray and Illumina BeadChip are also available.

  2. Gene Expression Profiling by MassARRAY Multiplex System

    We perform multiplex assays using Sequenom MassARRAY MALDI-TOF MS system. The MassARRAY system enables highly accurate and sensitive, cost efficient assays. DNA methylation analyses are also available with the MassARRAY system.

  3. Gene Expression Profiling by Quantitative RT-PCR

    We perform gene expression profiling of specific genes by real-time RT-PCR. Tests in compliance with the reliability standard are available at your request.

Genome Mutation Analyses

  1. Genome Mutation Analysis with Genotyping/Mapping Array

    We perform measurements and analyses of SNPs, LOH, and CGH in human genomic DNA with Illumina Genotyping Arrays and Affymetrix Mapping Arrays. We are an authorized service provider of Illumina, Inc. (Illumina CSPro) and Affymetrix, Inc.

  2. Genome Mutation Analysis by MassARRAY Multiplex System

    We perform SNP genotyping with Sequenom MassARRAY MALDI-TOF MS system.
    The MassARRAY system allows highly accurate and sensitive assays.

  3. Genome Mutation Analysis by PCR

    We perform gene mutation analyses by base sequence measurement of specific genomic regions by PCR. Special analyses such as comparative analyses between tumor tissues (isolated by microdissection from histopathological specimens) and normal tissues are also available. Moreover, we can perform genome mutation analyses by direct sequence measurement to meet specific needs.

  4. Multiplex Genome Mutation Analysis

    We perform genome mutation analyses for drug metabolism using Affymetrix DMET™ Plus Array and Roche AmpliChip® CYP450 Test.

All of our research and studies are in strict adherence to the laws concerning protection and management of animals with full respect of the standards concerning care and management of test animals, and have been accepted and certified for animal welfare practices.

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